Gender-Differences in Mice Hypericin Plasma Levels Upon Long-Term Hypericum Administration
نویسندگان
چکیده
منابع مشابه
Gender-Differences in Mice Hypericin Plasma Levels Upon Long-Term Hypericum Administration
Hypericum perforatum (St John's wort) is a well known medicinal plant used in many pharmaceutical formulations and its main active compound is hypericin. The purpose of our study was to examine the plasma level of hypericin upon long term mice treatment with Hyperici herba extract. A reversible hyperthermia was recorded upon 2 hours of the extract administration, both in males and females. Hype...
متن کاملHypericin and pseudohypericin in some Hypericum species.
Hypericin and pseudohypericin were found in 27 of the 36 evaluated species from Hypericum L., belonging to 17 sections of the genus. Pseudohypericin is reported by us in 15 taxa for the first time. Most of the species contained both components and the amount of pseudohypericin usually exceeded that of hypericin. In H. hirsutum and H. empetrifolium only hypericin was found, whereas H. formosissi...
متن کاملEffect of Long Term-Administration of Aspartame on Sperm Quality, Testosterone and Oxidant Parameters in Mice
Introduction: Aspartame is the most famous and widely used artificial sweetener which is extensively used in food stuffs. Many controversial reports are presented on the toxisity of aspartame on different body tissues; nonetheles, little data is available about the the side effects of Aspartame on the reproductive system. The present study was conducted in order to evaluate the effects of aspar...
متن کاملThe effects of long-term leptin administration on morphometrical changes of mice testicular tissue
Objective(s):Leptin is a novel and interesting hormone for anyone trying to lose weight, but its effects on male gonad structure in longitudinal study is unknown. The present study was designed to explore morphometrical changes of mouse testicular tissue after long-term administration of leptin. Materials and Methods:Thirty healthy mature male mice were randomly assigned to either control (n=15...
متن کاملLong-term administration of olanzapine induces adiposity and increases hepatic fatty acid desaturation protein in female C57BL/6J mice
Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we investigated the hepatic fatty acid effects of olanzapine in female C57BL/6J mice fed a normal diet.Materials and Methods: Female C57BL/6J mice ora...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Open Natural Products Journal
سال: 2009
ISSN: 1874-8481
DOI: 10.2174/1874848100902010068